Identification and Validation of PCAT14 as Prognostic Biomarker in Prostate Cancer
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چکیده
منابع مشابه
Identification and Validation of PCAT14 as Prognostic Biomarker in Prostate Cancer1
Rapid advances in the discovery of long noncoding RNAs (lncRNAs) have identified lineage- and cancer-specific biomarkers that may be relevant in the clinical management of prostate cancer (PCa). Here we assembled and analyzed a large RNA-seq dataset, from 585 patient samples, including benign prostate tissue and both localized and metastatic PCa to discover and validate differentially expressed...
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Introduction: As a glycoprotein, Plasma Prostate-Specific Antigen (PSA) is mainly produced by prostate epithelial cells and is used as a major diagnostic tool for prostate cancer. A group of researchers relate the elevated number of estrogen receptors in breast cancer samples to the over-production of PSA in this type of cancer. Therefore, the present study aimed to determine the participants' ...
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PURPOSE This paper describes a process for the identification of genes that can report on the aggressiveness of prostate tumors and thereby add to the information provided by current pathologic analysis. MATERIALS AND METHODS Expression profiling data from over 100 laser capture microdissection derived samples from nonneoplastic epithelium; Gleason patterns 3, 4, and 5 and node metastasis pro...
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ژورنال
عنوان ژورنال: Neoplasia
سال: 2016
ISSN: 1476-5586
DOI: 10.1016/j.neo.2016.07.001